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If you know the medication marketed as lioresal, you should know that it is not the only medication with the active substance called baclofen.

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Limited pharmacokinetic data suggest that a lumbar-cisternal concentration gradient of about 4:1 is established along the neuroaxis during baclofen infusionThis is based upon simultaneous CSF sampling via cisternal and lumbar tap in 5 patients receiving continuous baclofen infusion at the lumbar level at doses associated with therapeutic efficacythe interpatient variability was greatThe gradient was not altered by position.

Lioresal should be used with caution where spasticity is utilized to sustain upright posture and balance in locomotion or whenever spasticity is utilized to obtain increased function.

This medication has been prescribed for your current condition onlyDo not use it later for another condition unless your doctor directs you to do soA different medication may be necessary in that case.

If you miss a dosetake it as soon as you rememberIf it is near the time of the next doseskip themissed doseTake your next dose at the regular timeDo not double the dose to catch up.

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